Per-application settings are not supported with Application.cfm
December 5th, 2007
I was trying to integrate a legacy application with a new ColdFusion 8 application by creating mappings to my components in the new application. Unfortunately my old application uses a Application.cfm page and this is only possible if I use Application.cfc. Guess I am going to have to do some porting. See the following quote from the ColdFusion documentation.
Per-application settings are supported in applications that use an Application.cfc file only, not in applications that use an Application.cfm file. The per-application settings do not work if you have disabled application variables in the Memory Variables page of the Administrator.
Reference
livedocs